General Cell Based Assays
Cayman Chemical DuP-697 asy Reagent 1ea
An alkaloid with anti-inflammatory activity reduces LPS-induced TNF-a release from and NO production in RAW 264.7 macrophages at 10 30 and 100 UM reduces paw swelling in a rat model of CFA-induced arthritis at 9 and 27 mg/kg reduces colonic inflammatory cytokine levels and maintains mucosal barrier function in a mouse model of DSS-induced colitis from 25-100 mg/kg
Cayman Chemical EstradIol ELISA KIt 480Wel
Cayman’s Estradiol ELISA Kit is a competitive assay that can be used for the quantification of estradiol in plasma and serum. This assay has a range of 0.61-10,000 pg/ml with a sensitivity of approximately 20 pg/ml (80% B/B0)
Cayman Chemical sPLA2 asy KIt 96Wel
Cayman’s sPLA2 Assay provides an accurate and convenient method for measurement of sPLA2 activity. This assay uses the 1,2-dithio analog of diheptanoyl phosphatidylcholine which serves as a substrate for most PLA2s with the exception of cPLA2. Upon hydrolysis of the thioester bond at the sn-2 position by PLA2, free thiols are detected using DTNB.
Cayman Chemical FFA asy Buffer 1ea
A WEE1 inhibitor (IC50 0.8 nM) reduces tumor volume in combination etoposide in a PDX mouse model of stomach cancer at 30 mg/kg per day
Cayman Chemical Pyruvate asy Detectr 1ea
An internal standard for the quantification of palmitoyl-L-carnitine by GC- or LC-MS
Cayman Chemical GlutathIon asy KIt 480Wel
Cayman’s GSH Assay utilizes a carefully optimized enzymatic recycling method for the quantification of GSH in a 96-well microplate format. It measures both GSH and GSSG to reflect total glutathione in a sample. The kit can also be used to measure only GSSG by following an alternative protocol. The GSH Assay can be used for plasma, tissue samples, and cultured cells with minimal sample processing.
Revvity Health Sciences Inc HTRF Human Phospho-STING (Ser366) Detection Kit, 50,000 Assay Points
HTRF Human Phospho-STING (Ser366) Detection Kit, 50,000 Assay Points
Eurofins Discoverx PathHunter eXpress CCR2 Total GPCR Internalization Assay, 10pl Kit. (93-0679E3CP5L)
The PathHunter CCR2 Total GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CCR2 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged CCR2 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the CCR2 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Pro-Collagen Type 1 Detection Kit Standard
HTRF Human Pro-Collagen Type 1 Detection Kit Standard